Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | USP2 | O75604 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 5/20 | 0.48 |
| ▸ | CASP7 | P55210 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12761821 | 0.85 | SLC16A3 (0.74) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12511762 | 0.84 | SLC16A3 (0.83) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL24983245 | 0.83 | SLC16A3 (0.58) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL762114 | 0.83 | SLC16A3 (0.58) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL45609 | 0.83 | SLC16A3 (1.00) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL29364862 | 0.83 | SLC16A3 (1.00) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL29370055 | 0.83 | SLC16A3 (0.70) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL194640 | 0.83 | SLC16A3 (0.70) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL10123976 | 0.83 | SLC16A3 (0.70) | SLC16A3MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL12331025 | 0.83 | SLC16A3 (0.70) | SLC16A3MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570654-B2 | Nanoluc suicide substrates | PROMEGA CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| US-20230382908-A1 | NANOLUC SUICIDE SUBSTRATES | PROMEGA CORPORATION | 2023-11-30 | — | — | US | disclosed |
| US-11655247-B2 | Nanoluc suicide substrates | PROMEGA CORPORATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-20190337939-A1 | NANOLUC SUICIDE SUBSTRATES | PROMEGA CORPORATION | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382908-A1 | NANOLUC SUICIDE SUBSTRATES | XIAP, NLN, BAD | SLC16A3 2966/4885MEN1 4181/4885KMT2A 2837/4885 |
| US-11655247-B2 | Nanoluc suicide substrates | XIAP, NLN, BAD | SLC16A3 2966/4885MEN1 4181/4885KMT2A 2837/4885 |
| US-12570654-B2 | Nanoluc suicide substrates | NR3C1, LUC7L2, L3MBTL1 | SLC16A3 1650/4885MEN1 3109/4885KMT2A 2080/4885 |
| US-20190337939-A1 | NANOLUC SUICIDE SUBSTRATES | XIAP, NLN, BAD | SLC16A3 2966/4885MEN1 4181/4885KMT2A 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.