Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21523060 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2GPR139GPR88 | |
| Hydrochloric Acid SCHEMBL21523049 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2GPR139GPR88 | |
| Hydrochloric Acid SCHEMBL21523053 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2GPR139GPR88 | |
| Hydrochloric Acid SCHEMBL21523052 | 0.99 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2GPR139GPR88 | |
| SCHEMBL21531699 | 0.88 | EPHX2 (0.55) | NPC1RAB9ASMN1; SMN2GPR88EPHX2 | |
| Hydrochloric Acid SCHEMBL21523048 | 0.87 | EPHX2 (0.54) | NPC1RAB9ASMN1; SMN2GPR88EPHX2 | |
| Hydrochloric Acid SCHEMBL21523046 | 0.87 | EPHX2 (0.54) | NPC1RAB9ASMN1; SMN2GPR88EPHX2 | |
| Hydrochloric Acid SCHEMBL21523045 | 0.87 | EPHX2 (0.54) | NPC1RAB9ASMN1; SMN2GPR88EPHX2 | |
| Hydrochloric Acid SCHEMBL21523066 | 0.87 | EPHX2 (0.54) | NPC1RAB9ASMN1; SMN2GPR88EPHX2 | |
| SCHEMBL21531705 | 0.80 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2GPR139EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330141-A1 | Compositions With A Cooling Effect | THE PROCTER & GAMBLE COMPANY | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330141-A1 | Compositions With A Cooling Effect | CUTA, FABP4, EBP | NPC1 2946/4885RAB9A 2546/4885SMN1; SMN2 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.