SCHEMBL2153174

SCHEMBL2153174

Nc1ccc(-c2ccc(N)cc2Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.54
TSHR P16473 3/20 0.54
TNKS2 Q9H2K2 1/20 0.49
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ALDH1A1 P00352 8/20 0.46
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
PDE7A Q13946 1/20 0.45
POLB P06746 1/20 0.44
CSNK2A1 P68400 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 2/20 0.42
THRB P10828 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
GAA P10253 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28626436 0.98 CYP3A4 (0.52) CYP3A4TSHRTNKS2CA1CA2
Methane SCHEMBL27412224 0.98 CYP3A4 (0.52) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL9732490 0.91 CYP3A4 (0.50) CYP3A4TSHRTNKS2CA1CA2
Water SCHEMBL11776592 0.89 CYP3A4 (0.48) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL14202693 0.87 CYP3A4 (0.52) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL16013681 0.87 CYP3A4 (0.46) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL7136627 0.86 AHR (0.57) CYP3A4TSHRALDH1A1TDP1TP53
SCHEMBL16014529 0.86 CSNK2A1 (0.58) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL30839727 0.85 CYP3A4 (0.65) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL302092 0.85 CYP3A4 (0.65) CYP3A4TSHRTNKS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12209168-B2 Polyurethane foam premixes containing halogenated olefin blowing agents and foams made from same HONEYWELL INTERNATIONAL INC. (US) 2025-01-28 US claimed
CN-110092882-A Method based on waste paint slag preparation flame retarded polyurethane-foam material 山东理工大学 2019-08-06 CN claimed
CN-105085855-A High-temperature-resistance high-rigidity high-tenacity polyurethane pouring material and application thereof AEROSPACE RES INST MATERIALS & PROC TECHNOLOGY 2015-11-25 CN claimed
CN-102985447-A Polyurethane-based photoinitiators COLOPLAST AS 2013-03-20 CN claimed
CN-102947349-A Hydrophilic gels from polyurethane-based photoinitiators COLOPLAST AS 2013-02-27 CN claimed
CN-101747486-B Light-induced shape-memory polymer and preparation method thereof UNIV ZHEJIANG 2011-09-28 CN claimed
CN-101747486-A Light-induced shape-memory polymer and preparation method thereof UNIV ZHEJIANG 2010-06-23 CN claimed
CN-101333280-A Method for preparing modified urethane elastomer UNIV TONGJI (CN) 2008-12-31 CN claimed
CN-101245088-A Diamine, and polyamic acid and polyimide prepared from diamine DAILY POLYMER CORP (CN) 2008-08-20 CN claimed
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN claimed
CN-101085867-A Polyamic acid composition, and liquid crystal alignment agent and alignment film using same DAILY POLYMER CORP (CN) 2007-12-12 CN claimed
WO-2006067380-A1 MARKING OF PIPES UPONOR INNOVATION AB (SE) 2006-06-29 WO claimed
EP-0541510-B1 Wholly aromatic polyamide copolymer TEIJIN LTD (JP) 1996-09-18 EP claimed
US-5006629-A Excellent heat, fire, chemical resistance; spinning and shaping stability; superior mechanical strength TEIJIN LIMITED (JP) 1991-04-09 US claimed
EP-0367535-A1 Wholly aromatic polyamide copolymer TEIJIN LIMITED (JP) 1990-05-09 EP claimed
JP-62079227-A None JP disclosed
JP-61188127-A None JP disclosed
US-4297099-A BY PENETRATION AND CROSSLINKING DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
EP-0005211-A2 Process for the preparation of 2,2'-dichlorohydrazobenzene CIBA-GEIGY AG (CH) 1979-11-14 EP disclosed
JP-S06277921-A 0001-01-01 JP disclosed