SCHEMBL302092

SCHEMBL302092

Nc1ccc(-c2ccc(N)cc2Cl)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.65
TSHR P16473 4/20 0.65
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
ALDH1A1 P00352 7/20 0.50
POLB P06746 2/20 0.50
PLA2G7 Q13093 1/20 0.48
ALOX15 P16050 2/20 0.48
THRB P10828 2/20 0.48
HPGD P15428 1/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
HSD17B10 Q99714 1/20 0.48
PDE7A Q13946 1/20 0.46
GAA P10253 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
HTT P42858 1/20 0.45
ITGB2 P05107 1/20 0.45
ICAM1 P05362 1/20 0.45
ITGAL P20701 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30839727 1.00 CYP3A4 (0.65) CYP3A4TSHRCA1CA2ALDH1A1
Hydrochloric Acid SCHEMBL5800872 0.97 CYP3A4 (0.62) CYP3A4TSHRCA1CA2ALDH1A1
Hydrochloric Acid SCHEMBL7531143 0.97 CYP3A4 (0.62) CYP3A4TSHRCA1CA2ALDH1A1
SCHEMBL31661394 0.90 CYP3A4 (0.61) CYP3A4TSHRCA1CA2ALDH1A1
SCHEMBL27186003 0.90 CYP3A4 (0.61) CYP3A4TSHRCA1CA2ALDH1A1
SCHEMBL14054914 0.90 ITGB2 (0.59) CYP3A4TSHRCA1CA2ALDH1A1
SCHEMBL7969110 0.88 PLA2G7 (0.66) CYP3A4TSHRCA1CA2ALDH1A1
SCHEMBL2153174 0.85 CYP3A4 (0.54) CYP3A4TSHRCA1CA2ALDH1A1
Hydrochloric Acid SCHEMBL28626436 0.83 CYP3A4 (0.52) CYP3A4TSHRCA1CA2ALDH1A1
Methane SCHEMBL27412224 0.83 CYP3A4 (0.52) CYP3A4TSHRCA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1786 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
WO-2025149744-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 WO claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
CN-120040699-A Covalent organic framework material and preparation method and application thereof 贵州师范学院 2025-05-27 CN claimed
CN-119683766-B Resource utilization equipment and method for dichlorodiphenyl amine salt production sewage 山东隆盛和助剂有限公司 2025-05-23 CN claimed
CN-119793331-A Continuous feeding device for producing dichlorobenzidine salt 山东隆盛和助剂有限公司 2025-04-11 CN claimed
CN-119683766-A Resource utilization equipment and method for dichlorodiphenyl amine salt production sewage 山东隆盛和助剂有限公司 2025-03-25 CN claimed
CN-222007367-U Sewage treatment system for dichloro-diphenyl-amine salt production 山东隆盛和助剂有限公司 2024-11-15 CN claimed
EP-0517513-B1 Production of pigments CIBA GEIGY AG (CH) 1996-09-18 EP claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed
EP-0541510-A2 Wholly aromatic polyamide copolymer TEIJIN LIMITED (JP) 1993-05-12 EP claimed
EP-0311560-A2 Pigment compositions based on acetoacetarylides CIBA-GEIGY AG (CH) 1989-04-12 EP claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US claimed
US-4123061-A PREPOLYMER OF A POLYETHER, A DIISOCYANATE AND A POLYOL AND POLYAMINE CURING AGENT ACUSHNET COMPANY (US) 1978-10-31 US claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed
US-4071390-A Method of coating flexible substrates with polyurethane-polyurea elastomers and products produced thereby PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-01-31 US claimed
US-4071492-A Polyurethane-urea elastomers based on propylene oxide-tetrahydrofuran copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-01-31 US claimed
US-3963681-A POLYETHERURETHANE COPOLYMERS BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS PUF60, MORF4L1, C9 CYP3A4 1622/4885TSHR 4502/4885CA1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.