Methane

Methane

SCHEMBL27412224

C.Nc1ccc(-c2ccc(N)cc2Cl)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.52
TSHR P16473 3/20 0.52
TNKS2 Q9H2K2 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
PDE7A Q13946 1/20 0.44
ALDH1A1 P00352 8/20 0.43
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.42
CSNK2A1 P68400 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 2/20 0.41
THRB P10828 1/20 0.41
CASP1 P29466 1/20 0.41
RECQL P46063 1/20 0.41
GAA P10253 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153174 0.98 CYP3A4 (0.54) CYP3A4TSHRTNKS2CA1CA2
Hydrochloric Acid SCHEMBL28626436 0.95 CYP3A4 (0.52) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL9732490 0.89 CYP3A4 (0.50) CYP3A4TSHRTNKS2CA1CA2
Water SCHEMBL11776592 0.87 CYP3A4 (0.48) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL14202693 0.85 CYP3A4 (0.52) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL16013681 0.85 CYP3A4 (0.46) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL16014529 0.84 CSNK2A1 (0.58) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL7136627 0.84 AHR (0.57) CYP3A4TSHRALDH1A1TDP1TP53
SCHEMBL30839727 0.83 CYP3A4 (0.65) CYP3A4TSHRTNKS2CA1CA2
SCHEMBL302092 0.83 CYP3A4 (0.65) CYP3A4TSHRTNKS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106750171-B Ventilative high-temperature-resistant glove leather polyurethane resin and preparation method 浙江华峰合成树脂有限公司 2019-11-08 CN claimed
CN-110373147-A A kind of high-weathering-resistance polyurethane adhesive and preparation method thereof 荆晓东 2019-10-25 CN claimed
CN-110305288-A A kind of High-abrasion-resistpolyurethane polyurethane elastomer solid tyre and preparation method thereof 荆晓东 2019-10-08 CN claimed
CN-106739397-B The preparation method of high-orientation absorbing material 青岛卓英社科技股份有限公司 2019-08-27 CN claimed
CN-107057010-B A method of doping core-shell structure copolymer microballoon prepares sound-absorbing material 哈尔滨工业大学 2019-08-23 CN claimed
CN-109721758-A Micro- air bag combination material of polyurethane suitable for construction at high temperature and preparation method thereof 山东一诺威体育产业有限公司 2019-05-07 CN claimed
CN-109134807-A A kind of vehicle seat and preparation method thereof 无锡豪派车业科技有限公司 2019-01-04 CN claimed
CN-109015341-A A kind of CMP planarization layer and preparation method thereof based on porous oxidation cerium 成都时代立夫科技有限公司 2018-12-18 CN claimed
CN-108859344-A A kind of composite water-proof construction and preparation method 杰心(成都)环境科技有限公司 2018-11-23 CN claimed
CN-108864921-A A kind of strong basis layer adaptability double-composition polyurethane waterproof paint and preparation method thereof 雨中情防水技术集团有限责任公司 2018-11-23 CN claimed
CN-102604031-B Preparation method and application of polyester polyurethane elastomer JINTAN KAIRUIYUAN PHOTOELECTRIC TECHNOLOGY CO LTD 2013-10-30 CN claimed
CN-102643529-B Polymer composite for bearing and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2013-10-16 CN claimed
CN-103304960-A Preparation method of co-continuous POSS (Polyhedral Oligomeric Silsesquioxane)-epoxy modified resin UNIV XIAMEN 2013-09-18 CN claimed
CN-103277599-A Elastomer composite sludge discharging rubber pipe and production process thereof AUTOMOBILE REPAIR FACTORY OF SINOHYDRO TIANJIN ENGINEERING CO LTD 2013-09-04 CN claimed
CN-103267179-A Elastomer composite mud absorption rubber tube and manufacturing technique thereof AUTOMOBILE REPAIR FACTORY OF SINOHYDRO TIANJIN ENGINEERING CO LTD 2013-08-28 CN claimed
CN-102618203-B Weather-resistant etherification caulked joint adhesive and preparation method thereof JIANGSU GESANGHUA PAINT CO LTD 2013-08-28 CN claimed
CN-103254756-A Polyurethane waterproof coating for railway bridges and preparation method thereof Zibo dexin lianbang chemical industry co ltd 2013-08-21 CN claimed
CN-102492357-B Anti-sticking and wear resistant polyurea coating and its preparation method Hunan xiangjiang paint group co ltd 2013-08-14 CN claimed
CN-103214648-A Wet type polyurethane joint material for thermal insulation for seabed oil and gas pipeline interface and preparation method of wet type polyurethane joint material CHINA NAT OFFSHORE OIL CORP 2013-07-24 CN claimed
CN-101899262-A Polyurethane-urea waterproof coating and preparation method thereof SHANGHAI INST TECHNOLOGY 2010-12-01 CN claimed