Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21532082 | 0.96 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16722618 | 0.90 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21675353 | 0.90 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21675110 | 0.86 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16721451 | 0.86 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16721611 | 0.86 | BRD4 (0.81) | BRD4NPC1 | |
| SCHEMBL16722086 | 0.84 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL16721618 | 0.83 | BRD4 (0.70) | BRD4NPC1 | |
| SCHEMBL21674893 | 0.83 | BRD4 (0.67) | BRD4NPC1 | |
| SCHEMBL16722085 | 0.83 | BRD4 (0.67) | BRD4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330233-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS, INC. | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330233-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD7 | BRD4 1/4885NPC1 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.