Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21532330 | 0.96 | BRD4 (0.66) | BRD4 | |
| SCHEMBL16721451 | 0.91 | BRD4 (0.69) | BRD4HPGDTSHR | |
| SCHEMBL21675110 | 0.91 | BRD4 (0.69) | BRD4HPGDTSHR | |
| SCHEMBL21675353 | 0.87 | BRD4 (0.74) | BRD4 | |
| SCHEMBL16722051 | 0.87 | BRD4 (0.74) | BRD4HPGDTSHRPOLB | |
| SCHEMBL16722618 | 0.87 | BRD4 (0.74) | BRD4 | |
| SCHEMBL16721508 | 0.85 | BRD4 (0.69) | BRD4TSHR | |
| SCHEMBL21675294 | 0.85 | BRD4 (0.69) | BRD4TSHR | |
| SCHEMBL16722663 | 0.84 | BRD4 (0.65) | BRD4HPGDTSHRPOLB | |
| SCHEMBL21675096 | 0.84 | BRD4 (0.65) | BRD4HPGDTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330233-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS, INC. | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330233-A1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD7 | BRD4 1/4885HPGD 3467/4885TSHR 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.