SCHEMBL21532333

SCHEMBL21532333

c1ccc(-c2nnc(-c3ccccc3)n2-c2ccc3c4ccccc4n(-c4cccc(-n5c6ccccc6c6cc7c(cc65)oc5ccccc57)c4)c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 5/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HSD17B10 Q99714 3/20 0.36
MAPT P10636 2/20 0.36
RGS12 O14924 1/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
TSHR P16473 1/20 0.36
SLC5A1 P13866 1/20 0.35
SLC5A2 P31639 1/20 0.35
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21532299 0.97 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532336 0.96 ALDH1A1 (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532695 0.96 ALDH1A1 (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532630 0.95 KDM4E (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532293 0.93 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532271 0.93 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532384 0.92 KDM4E (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532331 0.92 KDM4E (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532696 0.91 ALDH1A1 (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1
SCHEMBL21532316 0.91 ALDH1A1 (0.38) ALDH1A1HPGDSMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-10-12 US disclosed
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same CRY1, CCNT1, CCNA1 ALDH1A1 158/4885HPGD 3627/4885SMN1; SMN2 2430/4885
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, ARL1 ALDH1A1 283/4885HPGD 4204/4885SMN1; SMN2 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.