SCHEMBL21532380

SCHEMBL21532380

c1ccc(-c2nc(-c3ccccc3)n(-c3ccc4c(c3)c3ccccc3n4-c3cccc(-n4c5ccccc5c5cc6oc7ccccc7c6cc54)c3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAC2 P15153 1/20 0.32
RAC3 P60763 1/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
SLC5A1 P13866 1/20 0.32
SLC5A2 P31639 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21532369 0.96 SLC5A1 (0.33) SLC5A1SLC5A2KDM4EATML3MBTL1
SCHEMBL21532762 0.96 RAC2 (0.32) RAC2RAC3CDC42RAC1SLC5A1
SCHEMBL21532215 0.93 SMN1; SMN2 (0.32) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21532216 0.93 PTGER4 (0.34) KDM4EATML3MBTL1
SCHEMBL21532760 0.93 SLC5A1 (0.33) SLC5A1SLC5A2KDM4EATML3MBTL1
SCHEMBL21532595 0.91 RAC2 (0.33) RAC2RAC3CDC42RAC1SLC5A1
SCHEMBL21532230 0.89 PTGER4 (0.34) KDM4EATML3MBTL1
SCHEMBL21532223 0.89 SMN1; SMN2 (0.32) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17636666 0.88 KDM4E (0.41) RAC2RAC3CDC42RAC1KDM4E
SCHEMBL21532748 0.88 KMT2A (0.32) RAC2RAC3CDC42RAC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-10-12 US disclosed
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same CRY1, CCNT1, CCNA1 RAC2 2614/4885RAC3 3379/4885CDC42 3197/4885
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, ARL1 RAC2 2879/4885RAC3 3793/4885CDC42 3762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.