SCHEMBL21532663

SCHEMBL21532663

c1ccc(-c2nc(-c3cccc4c5ccccc5n(-c5ccccc5-n5c6ccccc6c6cc7oc8ccccc8c7cc65)c34)n(-c3ccccc3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 2/20 0.35
CA12 O43570 2/20 0.31
CA9 Q16790 2/20 0.31
KDM6B O15054 1/20 0.30
ABCC4 O15439 1/20 0.30
ABCB11 O95342 1/20 0.30
KDM5A P29375 1/20 0.30
BLVRB P30043 1/20 0.30
SCN5A Q14524 1/20 0.30
KCND3 Q9UK17 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21532429 0.96 KDM4A (0.35) KDM4ACA12CA9KDM6BABCC4
SCHEMBL21532131 0.94 KDM4A (0.34) KDM4ACA12CA9
SCHEMBL21532351 0.93 KDM4A (0.35) KDM4ACA12CA9KDM6BABCC4
SCHEMBL21532678 0.90 KDM4A (0.34) KDM4ACA12CA9
SCHEMBL21532672 0.90 PTGER4 (0.34) CA12CA9
SCHEMBL21532669 0.90 SMN1; SMN2 (0.32) CA12CA9
SCHEMBL21532222 0.89 KDM4A (0.35) KDM4ACA12CA9KDM6BABCC4
SCHEMBL21532479 0.89 NPC1 (0.31)
SCHEMBL21532692 0.87 SLC5A1 (0.32)
SCHEMBL21532595 0.87 RAC2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-10-12 US disclosed
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145825-B2 Condensed cyclic compound and organic light-emitting device including i he same CRY1, CCNT1, CCNA1 KDM4A 3618/4885CA12 2336/4885CA9 2655/4885
US-20190334095-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, ARL1 KDM4A 3304/4885CA12 2397/4885CA9 3038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.