SCHEMBL21532864

SCHEMBL21532864

CC1C=C(c2cnccc2N)C=CC1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
CYP2C19 P33261 1/20 0.35
GAA P10253 1/20 0.33
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB4 P30926 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRND Q07001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20629280 0.78 ALDH1A1 (0.40) CYP3A4GAA
SCHEMBL21092858 0.73 CYP2A6 (0.45) CYP1A2CYP3A4CYP11B1CYP11B2
SCHEMBL21846149 0.64 CYP19A1 (0.38) CYP1A2CYP3A4CYP2D6CYP2C9CYP11B1
SCHEMBL14040684 0.62
SCHEMBL12463815 0.62
SCHEMBL22328751 0.62 HSD17B10 (0.43) CYP3A4GAA
SCHEMBL17345755 0.61 WDR5 (0.41) CYP2C19
SCHEMBL18888324 0.61
SCHEMBL19048920 0.61 CYP2D6 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP11B1
SCHEMBL16040917 0.60 CCNC (0.45) CYP1A2CYP3A4CYP2D6CYP2C9CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3561894-A1 DIAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-10-30 EP disclosed