⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21023380 | 0.84 | — | — | |
| SCHEMBL24875399 | 0.78 | — | — | |
| SCHEMBL21789658 | 0.77 | — | — | |
| SCHEMBL24312241 | 0.75 | — | — | |
| SCHEMBL23195681 | 0.74 | — | — | |
| SCHEMBL28195313 | 0.73 | CTSD (0.30) | — | |
| SCHEMBL15612914 | 0.69 | — | — | |
| SCHEMBL28195130 | 0.66 | DGAT1 (0.36) | — | |
| SCHEMBL28218782 | 0.66 | — | — | |
| SCHEMBL27881722 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020034-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-2955181-B1 | TRICYCLIC PYRROLOPYRIDINE COMPOUND, AND JAK INHIBITOR | NISSAN CHEMICAL CORP (JP) | 2019-10-30 | — | — | EP | disclosed |