Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533488 | 0.89 | APEX1 (0.48) | TSHRNPSR1ALDH1A1PKMMEN1 | |
| SCHEMBL21533485 | 0.80 | HDAC1 (0.42) | TSHRNPSR1ALDH1A1PKMMEN1 | |
| SCHEMBL21533486 | 0.77 | APEX1 (0.47) | NPSR1MEN1KMT2ARAB9AATM | |
| SCHEMBL21533538 | 0.75 | TLR7 (0.39) | TSHRNPSR1ALDH1A1PKMMEN1 | |
| SCHEMBL21533484 | 0.73 | MEN1 (0.46) | TSHRNPSR1MEN1KMT2ARAB9A | |
| SCHEMBL9422768 | 0.66 | KDM4E (0.67) | ALDH1A1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL668252 | 0.65 | LMNA (0.66) | ALDH1A1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL295889 | 0.64 | PPARA (0.66) | RAB9AHDAC1SMN1; SMN2HPGD | |
| SCHEMBL5154811 | 0.64 | PSEN1 (0.58) | ALDH1A1MAPTSMN1; SMN2HPGDTP53 | |
| Hydrochloric Acid SCHEMBL7685353 | 0.62 | PPARA (0.64) | RAB9AHDAC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330167-A1 | ACTIVATORS OF HIV LATENCY | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330167-A1 | ACTIVATORS OF HIV LATENCY | NFATC1, EP300, CD69 | HCRTR1 1549/4885TSHR 4851/4885NPSR1 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.