⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21533541 | 0.89 | LMNA (0.69) | — | |
| SCHEMBL21533564 | 0.88 | — | — | |
| SCHEMBL21533575 | 0.88 | — | — | |
| SCHEMBL21533574 | 0.87 | — | — | |
| SCHEMBL21533619 | 0.86 | — | — | |
| SCHEMBL21533452 | 0.86 | NPC1 (0.74) | — | |
| SCHEMBL21533620 | 0.86 | — | — | |
| SCHEMBL21533621 | 0.85 | — | — | |
| SCHEMBL21533497 | 0.84 | — | — | |
| SCHEMBL21533543 | 0.81 | ATAD2 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330167-A1 | ACTIVATORS OF HIV LATENCY | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2019-10-31 | — | — | US | disclosed |