SCHEMBL21534044

SCHEMBL21534044

CC(C)c1c[nH]c(CCC(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.40
RIPK1 Q13546 1/20 0.32
HTR1D P28221 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23315141 0.75 DAO (0.43) DAO
SCHEMBL891278 0.74 HTR1D (0.32) DAOHTR1D
SCHEMBL21324872 0.73 DAO (0.42) DAOHTR1D
SCHEMBL21792121 0.72 PDPK1 (0.31) HTR1D
SCHEMBL24175339 0.68 MCL1 (0.32)
SCHEMBL19818708 0.66 DAO (0.30) DAO
SCHEMBL891353 0.64
SCHEMBL21690936 0.63 RIPK1 (0.32) RIPK1
SCHEMBL2621617 0.62 DAO (0.33) DAOHTR1D
SCHEMBL23467393 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190330210-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS CV6 THERAPEUTICS (NI) LIMITED (GB) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330210-A1 HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS DUT, TYMP, DPYD DAO 449/4885RIPK1 3869/4885HTR1D 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.