Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535065 | 0.99 | OPRM1 (0.39) | OPRM1OPRK1HTR2AHTR2CADRB2 | |
| SCHEMBL21534854 | 0.91 | OPRM1 (0.40) | OPRM1OPRK1HTR2AHTR2CADRB2 | |
| SCHEMBL21534894 | 0.90 | HTR2A (0.35) | OPRM1OPRK1HTR2AHTR2CADRB2 | |
| SCHEMBL21534891 | 0.90 | OPRM1 (0.40) | OPRM1OPRK1HTR2AHTR2CADRB2 | |
| SCHEMBL21534926 | 0.89 | HTR2A (0.38) | OPRM1OPRK1HTR2AHTR2CMAOB | |
| SCHEMBL21534903 | 0.89 | ADRB2 (0.48) | OPRM1OPRK1HTR2AHTR2CADRB2 | |
| SCHEMBL21535147 | 0.87 | IKBKE (0.38) | OPRM1OPRK1HTR2AHTR2CDYRK1A | |
| SCHEMBL21534972 | 0.87 | MAOB (0.39) | MAOBMAOA | |
| SCHEMBL21534922 | 0.86 | DYRK1A (0.40) | OPRM1OPRK1HTR2AHTR2CMAOB | |
| SCHEMBL21534621 | 0.86 | MAOB (0.39) | MAOBMAOACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |