Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | MELK | Q14680 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534854 | 0.90 | OPRM1 (0.40) | HTR2AHTR2COPRM1OPRK1CHRM4 | |
| SCHEMBL21535147 | 0.90 | IKBKE (0.38) | HTR2AHTR2CIKBKETBK1OPRM1 | |
| SCHEMBL21534693 | 0.90 | HTR2A (0.35) | HTR2AHTR2CIKBKETBK1CHRM4 | |
| SCHEMBL21534666 | 0.85 | CHRM4 (0.40) | OPRM1OPRK1CHRM4MAOBCHRM2 | |
| SCHEMBL21534635 | 0.85 | CHRM4 (0.40) | OPRM1OPRK1CHRM4MAOBCHRM2 | |
| SCHEMBL21534881 | 0.84 | OPRM1 (0.37) | HTR2AHTR2COPRM1OPRK1CHRM4 | |
| SCHEMBL21534991 | 0.84 | CHRM4 (0.40) | CHRM4MAOBCHRM2MAOACHRM5 | |
| SCHEMBL21534890 | 0.83 | HTR2A (0.38) | HTR2AHTR2COPRM1OPRK1CHRM4 | |
| SCHEMBL21534641 | 0.82 | OPRM1 (0.40) | HTR2AHTR2COPRM1OPRK1CHRM4 | |
| SCHEMBL21535065 | 0.81 | OPRM1 (0.39) | HTR2AHTR2COPRM1OPRK1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |