Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 5/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534822 | 0.87 | SPHK1 (0.41) | KDM4ELMNAMAPTPOLBMET | |
| SCHEMBL21534903 | 0.86 | ADRB2 (0.48) | HTR2AHTR2CPOLBHRH3 | |
| SCHEMBL21534879 | 0.85 | PDK2 (0.40) | KDM4ELMNAMAPTPOLBMET | |
| SCHEMBL21534833 | 0.84 | CHRM4 (0.41) | LMNAPOLBHRH3 | |
| SCHEMBL21534925 | 0.84 | PDK2 (0.37) | KDM4ELMNAMAPTHTR2AHTR2C | |
| SCHEMBL21534994 | 0.79 | MAOB (0.39) | KDM4ELMNAMAPTPOLBMET | |
| SCHEMBL21535065 | 0.79 | OPRM1 (0.39) | HTR2AHTR2C | |
| SCHEMBL21534641 | 0.78 | OPRM1 (0.40) | HTR2AHTR2C | |
| SCHEMBL16777321 | 0.78 | POLB (0.46) | POLBMETPDK2HCRTR1 | |
| SCHEMBL15537904 | 0.78 | POLB (0.46) | POLBMETPDK2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |