Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534822 | 0.90 | SPHK1 (0.41) | POLBMETSPHK1SPHK2KDM4E | |
| SCHEMBL21534898 | 0.85 | KDM4E (0.40) | PDK2POLBMETHSD11B1KDM4E | |
| SCHEMBL21534833 | 0.83 | CHRM4 (0.41) | POLBLMNA | |
| SCHEMBL21534994 | 0.82 | MAOB (0.39) | POLBMETSPHK1SPHK2KDM4E | |
| SCHEMBL21534910 | 0.80 | PDK2 (0.41) | PDK2POLBROCK2HSD11B1LMNA | |
| SCHEMBL21534925 | 0.80 | PDK2 (0.37) | PDK2POLBMETROCK2HSD11B1 | |
| SCHEMBL15537885 | 0.79 | POLB (0.47) | PDK2POLBMETSPHK1SPHK2 | |
| SCHEMBL15537889 | 0.79 | POLB (0.47) | PDK2POLBMETSPHK1SPHK2 | |
| SCHEMBL15539063 | 0.79 | POLB (0.47) | PDK2POLBMETSPHK1SPHK2 | |
| SCHEMBL21534848 | 0.79 | KDM1A (0.38) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |