Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.35 |
| ▸ | WNT1 | P04628 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 6/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535006 | 0.92 | DYRK1A (0.33) | DYRK1AWNT1CHRM4GSK3BCHRM2 | |
| SCHEMBL21534991 | 0.88 | CHRM4 (0.40) | DYRK1AWNT1CHRM4CHRM2CHRM5 | |
| SCHEMBL21534635 | 0.87 | CHRM4 (0.40) | DYRK1AWNT1CHRM4CHRM2CHRM5 | |
| SCHEMBL21534666 | 0.87 | CHRM4 (0.40) | DYRK1AWNT1CHRM4CHRM2CHRM5 | |
| SCHEMBL21534878 | 0.86 | DYRK1A (0.40) | DYRK1AWNT1CHRM4GSK3BCHRM2 | |
| SCHEMBL21534658 | 0.85 | DYRK1A (0.39) | DYRK1AWNT1CHRM4GSK3BCHRM2 | |
| SCHEMBL21534872 | 0.85 | CHRM4 (0.35) | DYRK1AWNT1CHRM4CHRM2CHRM5 | |
| SCHEMBL21535062 | 0.84 | OPRM1 (0.36) | DYRK1AWNT1CHRM4CHRM2CHRM5 | |
| SCHEMBL21534854 | 0.84 | OPRM1 (0.40) | DYRK1AWNT1CHRM4GSK3BCHRM2 | |
| SCHEMBL21534881 | 0.81 | OPRM1 (0.37) | DYRK1AWNT1CHRM4GSK3BCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |