Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21535062 | 0.99 | OPRM1 (0.36) | CHRM4OPRM1OPRK1KDM1ACHRM2 | |
| SCHEMBL21534991 | 0.91 | CHRM4 (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534635 | 0.90 | CHRM4 (0.40) | CHRM4OPRM1OPRK1CHRM2CHRM5 | |
| SCHEMBL21534666 | 0.90 | CHRM4 (0.40) | CHRM4OPRM1OPRK1CHRM2CHRM5 | |
| SCHEMBL21534848 | 0.89 | KDM1A (0.38) | OPRM1OPRK1KDM1ACHKAMAOB | |
| SCHEMBL21534963 | 0.88 | KDM1A (0.38) | OPRM1OPRK1KDM1ACHKAMAOB | |
| SCHEMBL21534911 | 0.85 | SMN1; SMN2 (0.35) | CHRM4OPRM1OPRK1KDM1AALOX5AP | |
| SCHEMBL21535170 | 0.85 | DYRK1A (0.35) | CHRM4OPRM1OPRK1CHRM2CHRM5 | |
| SCHEMBL21535094 | 0.84 | KDM1A (0.35) | OPRM1OPRK1KDM1AMAOBMAOA | |
| SCHEMBL21534854 | 0.84 | OPRM1 (0.40) | CHRM4OPRM1OPRK1CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |