SCHEMBL215367

SCHEMBL215367

CC(C)CCCC(C)OCCCCO

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
RARB P10826 1/20 0.33
PTPN1 P18031 1/20 0.32
BLM P54132 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215614 0.87 LMNA (0.39) LMNAPTPN1BLM
SCHEMBL27960321 0.85 SMN1; SMN2 (0.32) LMNAEPHX2
SCHEMBL7943134 0.83 SMN1; SMN2 (0.44) LMNAEPHX2
SCHEMBL23097684 0.82 EPHX2 (0.33) LMNAEPHX2
SCHEMBL29892290 0.82 SMN1; SMN2 (0.37) LMNAEPHX2
SCHEMBL27203930 0.82 ALOX5 (0.33) EPHX2
SCHEMBL29892792 0.82 EPHX2 (0.33) LMNAEPHX2
SCHEMBL7940982 0.82 LMNA (0.46) LMNAEPHX2
SCHEMBL29891804 0.82 SMN1; SMN2 (0.42) LMNAEPHX2
SCHEMBL9011650 0.82 ALOX5 (0.33) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2514812-B1 Fragrance compositions and compounds GIVAUDAN SA (CH) 2018-10-03 EP disclosed
EP-2514812-A2 Fragrance compositions and compounds Givaudan Nederland Services B.V. (NL) 2012-10-24 EP disclosed
EP-2514812-A2 Fragrance compositions and compounds Givaudan Nederland Services B.V. (NL) 2012-10-24 EP disclosed
US-8088725-B2 Fragrance compositions and compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2012-01-03 US disclosed
US-20100132249-A1 Fragrance Compositions and Compounds GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2010-06-03 US disclosed
EP-2118249-A2 FRAGRANCE COMPOSITIONS AND COMPOUNDS Givaudan Nederland Services B.V. (NL) 2009-11-18 EP disclosed
WO-2008092678-A2 FRAGRANCE COMPOSITIONS AND COMPOUNDS GIVAUDAN NEDERLAND SERVICES B.V. (NL) 2008-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100132249-A1 Fragrance Compositions and Compounds H1-0, H1-10, H1-5 LMNA 2425/4885RARB 918/4885PTPN1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.