Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628238 | 0.72 | CYP2C19 (0.30) | — | |
| SCHEMBL1458781 | 0.72 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL225900 | 0.72 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL7018600 | 0.72 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL17386420 | 0.72 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL3831089 | 0.72 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL31095486 | 0.70 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL27764954 | 0.70 | EPHX1 (0.31) | HSD11B1 | |
| SCHEMBL10390936 | 0.70 | CYP3A4 (0.42) | HSD11B1 | |
| SCHEMBL28639116 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519532-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082192-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-07 | — | — | WO | disclosed |