Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386420 | 1.00 | HSD11B1 (0.34) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL1458781 | 1.00 | HSD11B1 (0.34) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL225900 | 1.00 | HSD11B1 (0.34) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL3831089 | 1.00 | HSD11B1 (0.34) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL31095486 | 0.98 | HSD11B1 (0.33) | HSD11B1LMNATSHRCES2CES1 | |
| Benzene SCHEMBL27333575 | 0.96 | HSD11B1 (0.33) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL571727 | 0.90 | LMNA (0.36) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL11593269 | 0.90 | LMNA (0.36) | HSD11B1LMNATSHRCES2CES1 | |
| SCHEMBL5029377 | 0.90 | GRM2 (0.33) | HSD11B1LMNATSHRGRM2GRM3 | |
| SCHEMBL9657672 | 0.86 | GRM2 (0.33) | LMNATSHRCES2CES1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856025-B1 | CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE | CELANESE VENTURES GMBH (DE) | 2003-01-15 | — | — | EP | claimed |
| US-6107447-A | LIQUID CRYSTALLINE POLYMERS | HOECHST RESEARCH TECHNOLOGY DEUTCHLAND GMBH & CO. KG (DE) | 2000-08-22 | — | — | US | disclosed |