Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18464324 | 0.94 | DHODH (0.44) | PDE3BPDE3APDK2DHODHMEN1 | |
| SCHEMBL21935453 | 0.89 | PDE3B (0.38) | PDE3BPDE3ARPS6KA3DHODHALOX5AP | |
| SCHEMBL18464327 | 0.88 | ESR1 (0.39) | PDE3BPDE3ARPS6KA3PDK2DHODH | |
| SCHEMBL18464129 | 0.88 | CYP2A6 (0.38) | PDE3BPDE3ARPS6KA3DHODHSMN1; SMN2 | |
| SCHEMBL14515087 | 0.85 | DHODH (0.42) | PDE3BPDE3APDK2DHODHCYP11B1 | |
| SCHEMBL12315382 | 0.84 | PTGS2 (0.44) | PDE3BPDE3ARPS6KA3PDK2DHODH | |
| SCHEMBL21134114 | 0.83 | CYP11B1 (0.45) | RPS6KA3PDK2CYP11B1CYP11B2NPC1 | |
| SCHEMBL18464325 | 0.82 | DHODH (0.46) | PDE3BPDE3APDK2DHODHMEN1 | |
| SCHEMBL20806197 | 0.82 | TNKS (0.34) | PDK2DHODHRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL20647415 | 0.81 | PDE3B (0.39) | PDE3BPDE3ARPS6KA3DHODHPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-3623451-B1 | COMPOUND | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3623451-A1 | COMPOUND | Merck Patent GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| EP-3129829-B1 | LIQUID CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2019-10-30 | — | — | EP | disclosed |