Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456624 | 0.92 | CYP11B1 (0.40) | CYP11B1CYP11B2RPS6KA3PDK2APP | |
| SCHEMBL25070289 | 0.90 | HSD17B1 (0.47) | CYP11B1CYP11B2CYP2C19NPC1RAB9A | |
| SCHEMBL19636766 | 0.89 | RARA (0.45) | CYP11B1CYP11B2CYP2C19POLBL3MBTL1 | |
| SCHEMBL19682268 | 0.89 | APP (0.41) | CYP11B1CYP11B2RPS6KA3PDK2APP | |
| SCHEMBL19456617 | 0.88 | GABRA1 (0.42) | CYP11B1CYP11B2PDK2POLBL3MBTL1 | |
| SCHEMBL21537510 | 0.83 | PDE3B (0.38) | CYP11B1CYP11B2RPS6KA3PDK2L3MBTL1 | |
| SCHEMBL22022025 | 0.82 | APP (0.45) | RPS6KA3APPCYP2C19ABCB1ABL1 | |
| SCHEMBL16265191 | 0.82 | RARB (0.48) | CYP2C19POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14515087 | 0.81 | DHODH (0.42) | CYP11B1CYP11B2PDK2L3MBTL1NPC1 | |
| SCHEMBL22238933 | 0.80 | CASP3 (0.41) | APPCYP2C19L3MBTL1MAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-3458549-B1 | LIQUID-CRYSTAL MATERIAL | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400271-B1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| EP-3400270-B1 | DEVICE FOR REGULATING ENTRY OF LIGHT | MERCK PATENT GMBH (DE) | 2020-04-29 | — | — | EP | disclosed |
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | CRY1, SLC25A1, CRY2 | CYP11B1 499/4885CYP11B2 329/4885RPS6KA3 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.