Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21650968 | 0.94 | MEN1 (0.62) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL21164680 | 0.88 | KDM4E (0.64) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL18182089 | 0.88 | KDM4E (0.67) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL9830022 | 0.87 | KDM4E (0.68) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL13256755 | 0.87 | KDM4E (0.62) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL20125154 | 0.84 | MEN1 (0.57) | KDM4ETSHRTP53ALDH1A1GAA | |
| SCHEMBL18177824 | 0.84 | KDM4E (0.62) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| SCHEMBL7300721 | 0.83 | CYP1A2 (0.62) | KDM4ETSHRTP53NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7563307 | 0.82 | NR1H2 (0.55) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL15828705 | 0.81 | ALDH1A1 (0.54) | KDM4ETSHRALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3561077-B1 | METHODS FOR CELL-PROLIFERATION-RELATED DISORDERS | SERVIER LAB (FR) | 2022-12-21 | — | — | EP | disclosed |
| EP-3561077-A1 | METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS | Agios Pharmaceuticals, Inc. (US) | 2019-10-30 | — | — | EP | disclosed |