Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879726 | 0.87 | KDM4E (0.68) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL17080715 | 0.85 | LMNA (0.60) | MEN1KMT2AGAAKDM4ETDP1 | |
| SCHEMBL21538245 | 0.84 | KDM4E (0.67) | MEN1KMT2APOLBGAAKDM4E | |
| Hydrochloric Acid SCHEMBL7563307 | 0.82 | NR1H2 (0.55) | MEN1KMT2APOLBGAAKDM4E | |
| SCHEMBL15828705 | 0.81 | ALDH1A1 (0.54) | MEN1KMT2APOLBGAAKDM4E | |
| SCHEMBL17982847 | 0.81 | GAA (0.56) | MEN1KMT2APOLBGAAKDM4E | |
| SCHEMBL13303563 | 0.80 | POLB (0.55) | KMT2APOLBKDM4ETDP1DRD2 | |
| SCHEMBL17982837 | 0.80 | RXFP1 (0.55) | MEN1KMT2APOLBGAAKDM4E | |
| SCHEMBL21650968 | 0.80 | MEN1 (0.62) | MEN1KMT2APOLBKDM4ETDP1 | |
| SCHEMBL29953304 | 0.80 | GAA (0.54) | MEN1KMT2APOLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |