Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815340 | 0.80 | ALDH1A1 (0.60) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL30764354 | 0.80 | ALDH1A1 (0.60) | NPC1POLBRAB9AALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL8856298 | 0.78 | ALDH1A1 (0.58) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL1773944 | 0.77 | NPC1 (0.55) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL2170490 | 0.75 | NPC1 (0.63) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL18805060 | 0.75 | NPC1 (0.63) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL20591233 | 0.74 | ALDH1A1 (0.68) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL30743 | 0.74 | NPC1 (1.00) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL29757180 | 0.74 | NPC1 (1.00) | NPC1POLBRAB9AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30444610 | 0.73 | NPC1 (0.61) | NPC1POLBRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560920-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | Janssen Pharmaceutica NV (BE) | 2019-10-30 | — | — | EP | disclosed |