Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805060 | 1.00 | NPC1 (0.63) | NPC1POLBRAB9AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30444610 | 0.98 | NPC1 (0.61) | NPC1POLBRAB9AALDH1A1MAPT | |
| Ethane SCHEMBL27315969 | 0.96 | ALDH1A1 (0.60) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL28790 | 0.92 | NPC1 (0.55) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL5174858 | 0.84 | NPC1 (0.78) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL30340895 | 0.84 | NPC1 (0.78) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL5176465 | 0.83 | NPC1 (0.75) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL3677458 | 0.83 | ALDH1A1 (0.59) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL29714436 | 0.83 | ALDH1A1 (0.59) | NPC1POLBRAB9AALDH1A1MAPT | |
| SCHEMBL31061957 | 0.82 | NPC1 (0.42) | NPC1POLBRAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003449-B | Synthesis method of tetrahydroquinoline compound with C-B bond | 广东以色列理工学院 | 2025-02-28 | — | — | CN | claimed |
| CN-118126272-A | Preparation and application of novel transfer hydrogenation catalyst | 中国人民武装警察部队后勤学院 | 2024-06-04 | — | — | CN | claimed |
| CN-117497827-A | Secondary battery and electricity utilization device | 东莞新能源科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| EP-4117436-A1 | METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA | Syngenta Crop Protection AG (CH) | 2023-01-18 | — | — | EP | claimed |
| CN-108107142-B | Analysis method of surfactant in wax removal water | 上海微谱化工技术服务有限公司 | 2020-05-22 | — | — | CN | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-10077261-B2 | Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer | JANSSEN PHARMACEUTICA NV (BE) | 2018-09-18 | — | — | US | claimed |
| EP-2892892-B1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SYNTHASE (FASN) INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-31 | — | — | EP | claimed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | claimed |
| US-20160002219-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2016-01-07 | — | — | US | claimed |
| EP-2892892-A1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SNTHASE (FASN) INHIBITORS FOR!THE TREATMENT OF CANCER | Janssen Pharmaceutica N.V. (BE) | 2015-07-15 | — | — | EP | claimed |
| US-20150099730-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA, NV (BE) | 2015-04-09 | — | — | US | claimed |
| WO-2014039769-A1 | IMIDAZOLIN-5-ONE DERIVATIVES USEFUL AS FATTY ACID SNTHASE (FASN) INHIBITORS FOR|THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2014-03-13 | — | — | WO | claimed |
| CN-1097751-A | The 6-fluoro quinoline keto-acid antibiotic derivative | NANJING INST OF MATERIA MEDICA (CN) | 1995-01-25 | — | — | CN | claimed |
| CN-120058445-A | Method for generating aryl phenol compound by hydroxylation of uranium photocatalytic aryl fluorine compound and application of method | 华东师范大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-119931978-A | Application of monoamine oxidase as catalyst in preparation of quinoline nitrogen heterocyclic compound | 河北工业大学 | 2025-05-06 | — | — | CN | disclosed |
| WO-2025077767-A1 | NOVEL I-TYPE TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |
| US-4308390-A | Process for the production of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1981-12-29 | — | — | US | disclosed |
| EP-0034279-A2 | Sulfoalkylating agents, process for their preparation and their use in the manufacture of quanternary sulfoalkyl salts | Agfa-Gevaert AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| US-4207320-A | FUNGICIDES | WARNER-LAMBERT COMPANY (US) | 1980-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099730-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | FASN, PLIN1, FABP1 | NPC1 969/4885POLB 3173/4885RAB9A 1530/4885 |
| US-10077261-B2 | Imidazolin-5-one derivative useful as FASN inhibitors for the treatment of cancer | FASN, PLIN1, FABP1 | NPC1 969/4885POLB 3173/4885RAB9A 1530/4885 |
| US-20160002219-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | FASN, PLIN1, FABP1 | NPC1 969/4885POLB 3173/4885RAB9A 1530/4885 |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | NPC1 917/4885POLB 1829/4885RAB9A 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.