SCHEMBL21539895

CC(C)(C)C(=O)OCSP(=O)(O)OCC1OC(n2cnc3c(=O)[nH]c(N)nc32)C[C@@H]1OP(=O)(OCC1CCC(n2cnc3c(N)ncnc32)O1)SCOC(=O)C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TERT	O14746	1/20	0.44

▸	POLB	P06746	2/20	0.44

▸	F2	P00734	2/20	0.41

▸	DTYMK	P23919	2/20	0.40

▸	FUT5	Q11128	1/20	0.39

▸	P2RY2	P41231	1/20	0.39

▸	P2RY4	P51582	1/20	0.39

▸	P2RY6	Q15077	1/20	0.39

▸	ENPP1	P22413	1/20	0.39

▸	P2RY1	P47900	1/20	0.39

▸	STING1	Q86WV6	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21540011	0.93	ALDH1A1 (0.42)	TERTPOLBDTYMKENPP1P2RY1
SCHEMBL21540007	0.89	STING1 (0.42)	STING1
SCHEMBL21417335	0.89	STING1 (0.42)	STING1
SCHEMBL21539918	0.84	STING1 (0.47)	POLBP2RY2P2RY1STING1
SCHEMBL21540009	0.83	TERT (0.53)	TERTPOLBFUT5P2RY2P2RY4
SCHEMBL20325223	0.83	TERT (0.53)	TERTPOLBFUT5P2RY2P2RY4
SCHEMBL20782764	0.83	TERT (0.53)	TERTPOLBFUT5P2RY2P2RY4
SCHEMBL20324868	0.83	TERT (0.53)	TERTPOLBFUT5P2RY2P2RY4
SCHEMBL18822882	0.82	TERT (0.52)	TERTPOLBF2DTYMKFUT5
SCHEMBL26570660	0.82	TERT (0.52)	TERTPOLBDTYMKFUT5P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3233882-B1	FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION	KAYLA THERAPEUTICS (FR)	2019-10-30	—	—	EP	disclosed