SCHEMBL21539964

SCHEMBL21539964

CC1CC=Cc2cc3cccc(N)c3cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
HPGD P15428 3/20 0.34
HSD17B10 Q99714 3/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
KEAP1 Q14145 1/20 0.34
F2 P00734 1/20 0.33
PLG P00747 1/20 0.33
PLAU P00749 1/20 0.33
PLAT P00750 1/20 0.33
KLK1 P06870 1/20 0.33
PRSS1 P07477 1/20 0.33
KDM4E B2RXH2 3/20 0.32
POLB P06746 3/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
TDP2 O95551 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CASP6 P55212 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5025415 0.79 CYP2A6 (0.33) TDP1NPC1LMNARAB9A
SCHEMBL10878544 0.76 TDP1 (0.31) ALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL13210457 0.73 CYP3A4 (0.33) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL21387956 0.73 CHRNB2 (0.37) ALDH1A1CYP3A4
SCHEMBL24612982 0.69 CA12 (0.37) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL24521865 0.68
SCHEMBL2874247 0.67 CHRNB2 (0.38) TDP1
SCHEMBL24832152 0.67 POLB (0.33) POLB
SCHEMBL23783792 0.67 AHR (0.47) ALDH1A1HPGDHSD17B10KDM4EKMT2A
SCHEMBL5545202 0.67 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3406597-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2019-10-30 EP disclosed