Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.62 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287586 | 0.89 | PRKCI (0.59) | PRKCIPRMT6LOXL2HTR7HRH3 | |
| SCHEMBL15244883 | 0.86 | TAAR1 (0.63) | LOXL2HTR7TAAR1MAOBDRD2 | |
| SCHEMBL301749 | 0.85 | PRKCI (0.67) | PRKCIPRMT6LOXL2TAAR1HRH3 | |
| SCHEMBL172787 | 0.84 | TAAR1 (0.62) | LOXL2HTR7TAAR1MAOBDRD2 | |
| Hydrochloric Acid SCHEMBL970902 | 0.83 | PRKCI (0.65) | PRKCIPRMT6LOXL2TAAR1HRH3 | |
| Hydrochloric Acid SCHEMBL972408 | 0.83 | PRKCI (0.65) | PRKCIPRMT6LOXL2TAAR1HRH3 | |
| Hydrochloric Acid SCHEMBL27718613 | 0.82 | HTR7 (0.61) | LOXL2HTR7TAAR1MAOBDRD2 | |
| SCHEMBL5216350 | 0.82 | CHRNA7 (0.65) | PRMT6LOXL2HTR7TAAR1DRD2 | |
| SCHEMBL15244935 | 0.82 | TAAR1 (0.51) | PRKCIHTR7TAAR1MAOBDRD2 | |
| SCHEMBL1138646 | 0.81 | PRKCI (0.73) | PRKCIPRMT6HRH3CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654834-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, FFAR1, FFAR3 | PRKCI 2168/4885PRMT6 3894/4885LOXL2 3118/4885 |
| US-10654834-B2 | Non-systemic TGR5 agonists | GPR119, SSTR5, FFAR3 | PRKCI 2388/4885PRMT6 3547/4885LOXL2 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.