Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21540588 | 0.91 | HIF1A (0.63) | HIF1ASLC29A1 | |
| SCHEMBL14616841 | 0.89 | HIF1A (0.53) | HIF1ASLC29A1 | |
| SCHEMBL548570 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL6267089 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL548569 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL23982373 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL21011280 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL6267085 | 0.88 | HIF1A (0.71) | HIF1ASLC29A1 | |
| SCHEMBL2288240 | 0.86 | HIF1A (0.68) | HIF1ASLC29A1 | |
| SCHEMBL2288246 | 0.86 | HIF1A (0.68) | HIF1ASLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654834-B2 | Non-systemic TGR5 agonists | Venenum Biodesign, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | Venenum Biodesign, LLC (US) | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330191-A1 | NOVEL NON-SYSTEMIC TGR5 AGONISTS | GPR119, FFAR1, FFAR3 | HIF1A 3486/4885SLC29A1 661/4885 |
| US-10654834-B2 | Non-systemic TGR5 agonists | GPR119, SSTR5, FFAR3 | HIF1A 3473/4885SLC29A1 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.