SCHEMBL548569

SCHEMBL548569

CNc1ncnc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.71
ADORA3 P0DMS8 1/20 0.67
SLC29A1 Q99808 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23982373 1.00 HIF1A (0.71) HIF1AADORA3SLC29A1
SCHEMBL21011280 1.00 HIF1A (0.71) HIF1AADORA3SLC29A1
SCHEMBL6267089 1.00 HIF1A (0.71) HIF1AADORA3SLC29A1
SCHEMBL548570 1.00 HIF1A (0.71) HIF1AADORA3SLC29A1
SCHEMBL6267085 1.00 HIF1A (0.71) HIF1AADORA3SLC29A1
SCHEMBL17920432 0.91 ADORA3 (0.67) HIF1AADORA3SLC29A1
SCHEMBL11986894 0.91 ADORA3 (0.67) HIF1AADORA3SLC29A1
SCHEMBL28912656 0.90 ADORA3 (0.69) HIF1AADORA3SLC29A1
SCHEMBL2288240 0.89 HIF1A (0.68) HIF1AADORA3SLC29A1
SCHEMBL2288246 0.89 HIF1A (0.68) HIF1AADORA3SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
CN-116445402-B Erythroid progenitor cell expansion culture medium, expansion culture method and application 中国科学院生态环境研究中心 2025-04-25 CN claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
EP-4493729-A1 METHODS FOR CHARACTERIZATION OF VIRAL GENOME USING BASE MODIFICATIONS Regeneron Pharmaceuticals, Inc. (US) 2025-01-22 EP claimed
CN-119072547-A Method for characterizing viral genomes using base modifications 瑞泽恩制药公司 2024-12-03 CN claimed
WO-2024069235-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2024-04-04 WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
WO-2021144475-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2021-07-22 WO claimed
CN-112778388-A Nucleoside analogue and preparation method and application thereof 大连医科大学 2021-05-11 CN claimed
CN-112770741-A Marker for determining sensitivity to combined anticancer agent 学校法人庆应义塾 2021-05-07 CN claimed
WO-2020067228-A1 MARKER FOR ASSESSING SENSITIVITY TO COMBINATION ANTICANCER DRUG 学校法人慶應義塾 2020-04-02 WO claimed
US-7510827-B2 Comprises nucleotide sequences probes and primers which hybridize flaviviral 3' untranslated regions for use as diagnostic tools in viral disease detection/infection; point mutations ROCHE MOLECULAR SYSTEMS, INC. (US) 2009-03-31 US claimed
EP-1611254-A2 COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP Roche Diagnostics GmbH (DE) 2006-01-04 EP claimed
US-20050032723-A1 Methods for increasing in vivo efficacy of oligonucleotides and inhibiting inflammation in mammals PHARMAXIS LTD (AU) 2005-02-10 US claimed
WO-2004092412-A2 COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP ROCHE DIAGNOSTICS GMBH (DE) 2004-10-28 WO claimed
EP-1406667-A2 METHODS FOR INCREASING i IN VIVO /i EFFICACY OF OLIGONUCLEOTIDES AND INHIBITING INFLAMMATION IN MAMMALS Topigen Pharmaceutiques Inc (CA) 2004-04-14 EP claimed
WO-2003004511-A2 METHODS FOR INCREASING IN VIVO EFFICACY OF OLIGONUCLEOTIDES AND INHIBITING INFLAMMATION IN MAMMALS TOPIGEN PHARMACEUTIQUE INC.. (CA) 2003-01-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT HIF1A 886/4885ADORA3 4335/4885SLC29A1 1862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.