SCHEMBL2154174

SCHEMBL2154174

CN(C)C([SiH3])(c1ccccc1)N(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.56
ALDH1A1 P00352 4/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP1A2 P05177 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
DRD2 P14416 1/20 0.35
DRD4 P21917 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1149712 0.76 KCNN4 (0.59) KCNN4ALDH1A1ESR1ESR2CYP3A4
Hydrochloric Acid SCHEMBL2810767 0.74 KCNN4 (0.56) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL2478431 0.72 KCNN4 (0.62) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL5921941 0.72 KCNN4 (1.00) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL6057002 0.72 KCNN4 (0.62) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL4649341 0.69 MAPK1 (0.50) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL859321 0.69 MAPK1 (0.50) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL307045 0.69 MAPK1 (0.50) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL14236873 0.68 KCNN4 (0.44) KCNN4ALDH1A1ESR1ESR2CYP3A4
SCHEMBL2956964 0.68 KCNN4 (0.56) KCNN4ALDH1A1ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250098186-A1 INTEGRATED CIRCUIT DEVICES AND METHODS OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2025-03-20 US disclosed
US-12199137-B2 Integrated circuit devices and methods of manufacturing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-01-14 US disclosed
US-20220416010-A1 INTEGRATED CIRCUIT DEVICES AND METHODS OF MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-12-29 US disclosed
US-10745497-B2 Aminosilane initiators and functionalized polymers prepared therefrom BRIDGESTONE CORPORATION (JP) 2020-08-18 US disclosed
EP-2519548-B1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORP (JP) 2020-04-01 EP disclosed
US-20190338052-A1 Processes For Preparing Aminosilane Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2019-11-07 US disclosed
US-10351636-B2 Processes for preparing aminosilane functionalized polymers BRIDGESTONE CORPORATION (JP) 2019-07-16 US disclosed
WO-2018150043-A1 METALLATED BENZYLSILANES AND THEIR USE AS POLYMERIZATION INITIATORS TRINSEO EUROPE GMBH (CH) 2018-08-23 WO disclosed
EP-3363804-A1 METALLATED BENZYLSILANES AND THEIR USE AS POLYMERIZATION INITIATORS Trinseo Europe GmbH (CH) 2018-08-22 EP disclosed
US-20180155460-A1 Aminosilane Initiators And Functionalized Polymers Prepared Therefrom BRIDGESTONE CORPORATION (JP) 2018-06-07 US disclosed
US-9255158-B2 Aminosilane initiators, functionalized polymers prepared therefrom and related processes BRIDGESTONE CORPORATION (JP) 2016-02-09 US disclosed
US-20150099852-A1 AMINOSILANE INITIATORS, FUNCTIONALIZED POLYMERS PREPARED THEREFROM AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2015-04-09 US disclosed
US-8916665-B2 Aminosilane initiators and functionalized polymers prepared therefrom BRIDGESTONE CORPORATION (JP) 2014-12-23 US disclosed
EP-2658727-B1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORP (JP) 2014-12-03 EP disclosed
EP-2658727-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM Bridgestone Corporation (JP) 2013-11-06 EP disclosed
US-20130281645-A1 Aminosilane Initiators And Functionalized Polymers Prepared Therefrom BRIDGESTONE CORPORATION (JP) 2013-10-24 US disclosed
US-20130066008-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORPORATION (JP) 2013-03-14 US disclosed
EP-2519548-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM Bridgestone Corporation (JP) 2012-11-07 EP disclosed
WO-2012091753-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
WO-2011082277-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM BRIDGESTONE CORPORATION (JP) 2011-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745497-B2 Aminosilane initiators and functionalized polymers prepared therefrom WEE1, WEE2, ITK KCNN4 4060/4885ALDH1A1 3720/4885ESR1 2452/4885
US-20130066008-A1 AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM WEE1, WEE2, ITK KCNN4 4060/4885ALDH1A1 3720/4885ESR1 2452/4885
US-20180155460-A1 Aminosilane Initiators And Functionalized Polymers Prepared Therefrom WEE1, WEE2, ITK KCNN4 4060/4885ALDH1A1 3720/4885ESR1 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.