Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859321 | 0.81 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL307045 | 0.81 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302136 | 0.79 | MAPK1 (0.48) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302535 | 0.77 | ALDH1A1 (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL9364930 | 0.77 | MAPK1 (0.46) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL15302768 | 0.77 | TSHR (0.52) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL10812897 | 0.75 | MAPK1 (0.50) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| SCHEMBL96177 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL22264597 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 | |
| Tert-Butylbenzene SCHEMBL22264599 | 0.73 | MAPK1 (0.55) | MAPK1ALDH1A1TAAR1ALOX15ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638144-A | Synthesis method of heteroaryl silane | 南阳师范学院 | 2024-09-13 | — | — | CN | claimed |
| CN-117865999-A | Preparation method of silicon-based benzazepine-ketone compound | 烟台大学 | 2024-04-12 | — | — | CN | claimed |
| CN-115954549-A | Magnesium battery electrolyte, preparation method and magnesium battery | 重庆长安新能源汽车科技有限公司 | 2023-04-11 | — | — | CN | claimed |
| US-10189867-B2 | Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same | Henkel IP & Holding GmbH (DE) | 2019-01-29 | — | — | US | claimed |
| EP-3186263-A1 | ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF | Henkel AG & Co. KGaA (DE) | 2017-07-05 | — | — | EP | claimed |
| US-20170166594-A1 | Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same | HENKEL (CHINA) COMPANY LIMITED (CN) | 2017-06-15 | — | — | US | claimed |
| US-9505718-B2 | 3-piperidone compounds and their use as neurokinin-1 (NK1) receptor antagonists | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-11-29 | — | — | US | claimed |
| WO-2016029439-A1 | ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF | HENKEL (CHINA) COMPANY LIMITED (CN) | 2016-03-03 | — | — | WO | claimed |
| US-20160031817-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-02-04 | — | — | US | claimed |
| WO-2014142761-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-09-18 | — | — | WO | claimed |
| EP-0458060-B1 | Agent for preserving wood and wooden materials | DESOWAG MATERIALSCHUTZ GMBH (DE) | 1995-10-11 | — | — | EP | claimed |
| EP-0458061-B1 | Agent for preserving wood and wooden materials | DESOWAG MATERIALSCHUTZ GMBH (DE) | 1995-10-11 | — | — | EP | claimed |
| US-4748262-A | (Phenyl dimethyl carbinyl) silane compound and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| CN-118496627-B | FRP composite material and preparation method and application thereof | 南京斯贝尔复合材料仪征有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118638144-A | Synthesis method of heteroaryl silane | 南阳师范学院 | 2024-09-13 | — | — | CN | disclosed |
| CN-118496627-A | FRP composite material and preparation method and application thereof | 南京斯贝尔复合材料仪征有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-0963996-A2 | Novel transition metal compound, catalyst component for olefin polymerization and process for the preparation of alpha-olefin polymer | Japan Polychem Corporation (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5516956-A | SILICA BINDERS FOR ZEOLITE CATALYSTS FOR ISOMERIZATION | MOBIL OIL CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| US-4748262-A | (Phenyl dimethyl carbinyl) silane compound and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4748262-A | (Phenyl dimethyl carbinyl) silane compound and a method for the preparation thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189867-B2 | Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same | ITGB2, ITGB8, C3AR1 | MAPK1 3496/4885ALDH1A1 1399/4885TAAR1 1153/4885 |
| US-20160031817-A1 | 3-PIPERIDONE COMPOUNDS AND THEIR USE AS NEUROKININ-1 (NK1) RECEPTOR ANTAGONISTS | TACR1, NPSR1, TACR2 | MAPK1 1117/4885ALDH1A1 1229/4885TAAR1 241/4885 |
| US-20170166594-A1 | Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same | ITGB2, ITGB8, C3AR1 | MAPK1 3581/4885ALDH1A1 1378/4885TAAR1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.