SCHEMBL859321

SCHEMBL859321

CC([SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 3/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALOX15 P16050 1/20 0.46
KCNN4 O15554 4/20 0.44
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 2/20 0.43
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
CYP2B6 P20813 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27660671 0.97 MAPK1 (0.48) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL307045 0.81 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL4649341 0.81 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL15302136 0.79 MAPK1 (0.48) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL15302535 0.77 ALDH1A1 (0.52) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL9364930 0.77 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL15302768 0.77 TSHR (0.52) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL10812897 0.75 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15KCNN4
Tert-Butylbenzene SCHEMBL18889 0.73 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15KCNN4
Tert-Butylbenzene SCHEMBL22264599 0.73 MAPK1 (0.55) MAPK1ALDH1A1TAAR1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
CN-1130382-C Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST IND TECHNOLOGY (CN) 2003-12-10 CN claimed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
US-5354340-A Preparation of copolymers SHELL OIL COMPANY (US) 1994-10-11 US claimed
CN-117355373-B Ethylene oligomerization process 切弗朗菲利浦化学公司 2025-05-16 CN disclosed
CN-116606300-B Amino compound, organic electroluminescent element and organic electroluminescent device 北京八亿时空液晶科技股份有限公司 2024-12-03 CN disclosed
CN-116655570-B Naphthofuran derivative and application thereof 北京八亿时空液晶科技股份有限公司 2024-08-02 CN disclosed
EP-3543263-B1 POLYOLEFIN-BASED EMULSIFIER AND APPLICATION THEREOF FOR PREPARING HIGH INTERNAL PHASE EMULSION AND POROUS POLYMERIC MATERIAL UNIV ZHEJIANG (CN) 2024-07-03 EP disclosed
CN-117355373-A Ethylene oligomerization process 切弗朗菲利浦化学公司 2024-01-05 CN disclosed
CN-116655570-A Naphthofuran derivative and application thereof 北京八亿时空液晶科技股份有限公司 2023-08-29 CN disclosed
CN-116606300-A Amino compound, organic electroluminescent element and organic electroluminescent device 北京八亿时空液晶科技股份有限公司 2023-08-18 CN disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
EP-0669952-B1 PREPARATION OF CARBON MONOXIDE POLYMERS SHELL INT RESEARCH (NL) 1997-03-12 EP disclosed
EP-0669952-A1 PREPARATION OF CARBON MONOXIDE POLYMERS. SHELL INT RESEARCH (NL) 1995-09-06 EP disclosed
US-5354340-A Preparation of copolymers SHELL OIL COMPANY (US) 1994-10-11 US disclosed
WO-1994012559-A1 PREPARATION OF CARBON MONOXIDE POLYMERS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-06-09 WO disclosed