Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 16/20 | 0.49 |
| ▸ | PRKDC | P78527 | 7/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | ATR | Q13535 | 5/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 5/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 6/20 | 0.35 |
| ▸ | SERPINA2 | P20848 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27124075 | 1.00 | ATM (0.49) | ATMPRKDCHRH4ATRATRIP | |
| SCHEMBL21541780 | 0.90 | ATM (0.51) | ATMPRKDCHRH4ATRATRIP | |
| SCHEMBL27123627 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPPIK3CB | |
| SCHEMBL21541906 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPPIK3CB | |
| SCHEMBL21541824 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPPIK3CB | |
| SCHEMBL27124026 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPPIK3CB | |
| SCHEMBL21541829 | 0.88 | ATM (0.63) | ATMPRKDCATRPIK3CBMTOR | |
| SCHEMBL27129299 | 0.88 | ATM (0.63) | ATMPRKDCATRPIK3CBMTOR | |
| SCHEMBL21541729 | 0.88 | ATM (0.45) | ATMPRKDCATRATRIPPIK3CB | |
| SCHEMBL20374560 | 0.88 | ATM (0.50) | ATMPRKDCATRATRIPPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | claimed |
| EP-3567041-A9 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-04-20 | — | — | EP | claimed |
| US-10874670-B2 | Substituted fused heteroaromatic compounds as kinase inhibitors and the use thereof | IMPACT THERAPEUTICS, INC. (CN) | 2020-12-29 | — | — | US | claimed |
| EP-3567041-A1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics, Inc (CN) | 2019-11-13 | — | — | EP | claimed |
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |
| EP-3567041-A9 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-04-20 | — | — | EP | disclosed |
| US-10874670-B2 | Substituted fused heteroaromatic compounds as kinase inhibitors and the use thereof | IMPACT THERAPEUTICS, INC. (CN) | 2020-12-29 | — | — | US | disclosed |
| EP-3567041-A1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics, Inc (CN) | 2019-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874670-B2 | Substituted fused heteroaromatic compounds as kinase inhibitors and the use thereof | CHEK1, CHEK2, CDK1 | ATM 35/4885PRKDC 61/4885HRH4 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.