Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 17/20 | 0.49 |
| ▸ | PRKDC | P78527 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 5/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 7/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.35 |
| ▸ | SERPINA2 | P20848 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541906 | 1.00 | ATM (0.49) | ATMPRKDCCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21541770 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL27124075 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL27123627 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL21541824 | 0.90 | ATM (0.49) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL21541829 | 0.88 | ATM (0.63) | ATMPRKDCATRMTORPIK3CB | |
| SCHEMBL27129299 | 0.88 | ATM (0.63) | ATMPRKDCATRMTORPIK3CB | |
| SCHEMBL21541736 | 0.88 | ATM (0.50) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL20374560 | 0.88 | ATM (0.50) | ATMPRKDCATRATRIPMTOR | |
| SCHEMBL21541756 | 0.88 | ATM (0.48) | ATMPRKDCATRATRIPMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |