Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.63 |
| ▸ | PRKDC | P78527 | 3/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.46 |
| ▸ | MTOR | P42345 | 11/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 3/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541829 | 1.00 | ATM (0.63) | ATMPRKDCPIK3CAMTORPIK3CD | |
| SCHEMBL20374560 | 0.90 | ATM (0.50) | ATMPRKDCPIK3CAMTORPIK3CB | |
| SCHEMBL21541736 | 0.90 | ATM (0.50) | ATMPRKDCPIK3CAMTORPIK3CB | |
| SCHEMBL27124075 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CD | |
| SCHEMBL21541906 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CD | |
| SCHEMBL27124026 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CD | |
| SCHEMBL21541824 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CB | |
| SCHEMBL21541770 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CD | |
| SCHEMBL27123627 | 0.88 | ATM (0.49) | ATMPRKDCPIK3CAMTORPIK3CB | |
| SCHEMBL23093868 | 0.88 | ATM (0.54) | ATMPRKDCPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | claimed |