SCHEMBL2154267

SCHEMBL2154267

CC(C)Oc1ccccc1C(=O)Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.68
ALDH1A1 P00352 3/20 0.50
ACHE P22303 1/20 0.50
IDO1 P14902 1/20 0.49
TDO2 P48775 1/20 0.49
KCNK3 O14649 2/20 0.47
KCNK9 Q9NPC2 2/20 0.47
ALOX15 P16050 1/20 0.44
KDM4E B2RXH2 3/20 0.43
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
PRMT5 O14744 1/20 0.42
MRGPRX1 Q96LB2 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CTSD P07339 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7088362 0.84 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2094692 0.84 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL28293902 0.82 IRAK4 (0.70) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL104892 0.82 IRAK4 (0.70) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL19924675 0.82 IRAK4 (0.47) IRAK4ALDH1A1IDO1TDO2ALOX15
SCHEMBL2103513 0.81 IRAK4 (1.00) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL16674268 0.81 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2094687 0.81 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
Bicarbonate SCHEMBL21811920 0.81 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL10763308 0.81 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082181-A PBAT/bamboo powder biodegradable composite master batch, preparation method thereof and composite film 国际竹藤中心 2025-06-03 CN claimed
CN-120082181-A PBAT/bamboo powder biodegradable composite master batch, preparation method thereof and composite film 国际竹藤中心 2025-06-03 CN disclosed
EP-2844345-B1 MODULATORS OF THE RELAXIN RECEPTOR 1 US HEALTH (US) 2022-08-03 EP disclosed
EP-3507271-B1 VERFAHREN ZUR HERSTELLUNG VON SALICYLOYL-L-CARNITIN-HYDROCHLORID DRUGON PHARMA SWITZERLAND AG (CH) 2021-09-29 EP disclosed
US-10723691-B2 Process for preparing salicyloyl-L-carnitine hydrochloride DRUG'ON PHARMA SWITZERLAND AG (CH) 2020-07-28 US disclosed
EP-3326999-B1 SALICYLOYLCARNITIN SULFONATES DRUGON PHARMA SWITZERLAND AG (CH) 2019-08-07 EP disclosed
EP-3507271-A1 PROCESS FOR PREPARING SALICYLOYL-L-CARNITINE HYDROCHLORIDE Drug'On Pharma Switzerland AG (CH) 2019-07-10 EP disclosed
US-20190202775-A1 PROCESS FOR PREPARING SALICYLOYL-L-CARNITINE HYDROCHLORIDE DRUG'ON PHARMA SWITZERLAND AG (CH) 2019-07-04 US disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
US-7332629-B2 Modulators (inhibitors/activators) of histone acetyltransferases JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2008-02-19 US disclosed
US-20060167107-A1 Modulators (inhibitors/ activators) of histone acetyltransferases JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2006-07-27 US disclosed
EP-1590318-A2 MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES Jawaharlal Nehru Centre For Advanced Scientific Research (IN) 2005-11-02 EP disclosed
WO-2004053140-A2 MODULATORS (INHIBITORS/ACTIVATORS) OF HISTONE ACETYLTRANSFERASES JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2004-06-24 WO disclosed
EP-0598756-B1 ESTER COMPOSITION SHELL INT RESEARCH (NL) 1996-06-05 EP disclosed
EP-0636626-A1 Pyrazolopyrimidine Derivatives LABORATOIRES GLAXO SA (FR) 1995-02-01 EP disclosed
US-5332858-A Esterification with active phenolic ether and chloroformyl group and active phenol SHELL OIL COMPANY (US) 1994-07-26 US disclosed
EP-0598756-A1 ESTER COMPOSITION. SHELL INT RESEARCH (NL) 1994-06-01 EP disclosed
WO-1993002038-A1 ESTER COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1993-02-04 WO disclosed
US-4251531-A ANTIALLERGENS FARMITALIA CARLO ERBA S.P.A. (IT) 1981-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202775-A1 PROCESS FOR PREPARING SALICYLOYL-L-CARNITINE HYDROCHLORIDE CRAT, CPT1B, MCCC2 IRAK4 954/4885ALDH1A1 859/4885ACHE 2077/4885
US-20060167107-A1 Modulators (inhibitors/ activators) of histone acetyltransferases EP300, HDAC1, KAT2A IRAK4 2407/4885ALDH1A1 962/4885ACHE 517/4885
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 IRAK4 4402/4885ALDH1A1 4849/4885ACHE 1107/4885
US-10723691-B2 Process for preparing salicyloyl-L-carnitine hydrochloride CRAT, CPT1B, MCCC2 IRAK4 954/4885ALDH1A1 859/4885ACHE 2077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.