Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14523837 | 0.85 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL1102401 | 0.84 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL3325166 | 0.83 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL12852111 | 0.83 | RAB9A (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11368923 | 0.82 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11697061 | 0.81 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL31170 | 0.80 | NPC1 (0.81) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL11695483 | 0.80 | MAOA (0.65) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL23079718 | 0.79 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL14030921 | 0.79 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573611-B1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO LTD (TW) | 2022-01-12 | — | — | EP | disclosed |
| EP-3573611-B1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO LTD (TW) | 2022-01-12 | — | — | EP | disclosed |
| US-10882837-B2 | Amide compounds and use thereof | ALPHALA CO., LTD. (TW) | 2021-01-05 | — | — | US | disclosed |
| US-10882837-B2 | Amide compounds and use thereof | ALPHALA CO., LTD. (TW) | 2021-01-05 | — | — | US | disclosed |
| US-20190345118-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2019-11-14 | — | — | US | disclosed |
| US-20190345118-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2019-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882837-B2 | Amide compounds and use thereof | GLP1R, IAPP, GCG | NPC1 822/4885RAB9A 744/4885MEN1 833/4885 |
| US-20190345118-A1 | AMIDE COMPOUNDS AND USE THEREOF | GLP1R, IAPP, GCG | NPC1 822/4885RAB9A 744/4885MEN1 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.