SCHEMBL2154602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL7280013	0.99	PDE5A (0.63)	PDE5ANPC1HTTRAB9AMAPK1
	SCHEMBL14726166	0.88	PDE5A (0.50)	PDE5ANPC1MAPK1KMT2ACYP1A2
	SCHEMBL14727426	0.88	PDE5A (0.53)	PDE5ANPC1HTTRAB9AKMT2A
	SCHEMBL16183305	0.86	GBA1 (0.49)	PDE5ANPC1HTTMAPK1KMT2A
	SCHEMBL15966763	0.86	CYP3A4 (0.57)	PDE5ANPC1MAPK1KMT2ACYP1A2
	SCHEMBL14726233	0.86	PDE5A (0.60)	PDE5ANPC1HTTRAB9AMAPK1
	SCHEMBL16183310	0.86	KMT2A (0.52)	PDE5ANPC1KMT2ACYP1A2CYP3A4
	SCHEMBL16183927	0.86	PDE5A (0.60)	PDE5ARAB9AMAPK1KMT2ACYP1A2
	Hydrochloric Acid SCHEMBL7280690	0.85	PDE5A (0.61)	PDE5ANPC1HTTRAB9AMAPK1
	Hydrochloric Acid SCHEMBL7280022	0.85	PDE5A (0.52)	PDE5ANPC1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.