Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546354 | 0.90 | HRH4 (0.39) | HRH4LIPEHDAC1CCKBRCNR1 | |
| SCHEMBL17620032 | 0.88 | HRH4 (0.36) | HRH4LIPEHDAC1CCKBRCNR1 | |
| SCHEMBL19403959 | 0.83 | HRH4 (0.45) | HRH4LIPECNR1TDP1 | |
| SCHEMBL18591494 | 0.81 | KDM4E (0.37) | HRH4HDAC1CCKBR | |
| SCHEMBL21546370 | 0.72 | GAA (0.42) | CCKBR | |
| SCHEMBL20791913 | 0.71 | CYP2D6 (0.38) | — | |
| SCHEMBL20791900 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL17619899 | 0.69 | WNT3A (0.38) | — | |
| SCHEMBL17619954 | 0.69 | PADI4 (0.36) | TDP1 | |
| SCHEMBL21546368 | 0.69 | PADI4 (0.36) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194030-B1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER INC (US) | 2019-11-06 | — | — | EP | disclosed |