Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546911 | 0.94 | ADRA2C (0.34) | ADRA2CBRD4ARPDK2PRF1 | |
| SCHEMBL22760693 | 0.92 | CHEK1 (0.37) | ADRA2CBRD4PTGER4PDK2PRF1 | |
| SCHEMBL22761142 | 0.90 | PTGER4 (0.33) | ADRA2CBRD4PTGER4ARPDK2 | |
| SCHEMBL21546900 | 0.90 | PGR (0.32) | ADRA2CBRD4ARPDK2CHEK1 | |
| SCHEMBL21546968 | 0.90 | CHEK1 (0.36) | ADRA2CPDK2PRF1ADORA2AADORA1 | |
| SCHEMBL22761078 | 0.89 | PDE9A (0.37) | PTGER4ARADORA2AADORA1ADORA2B | |
| SCHEMBL22761173 | 0.89 | SMN1; SMN2 (0.34) | ADRA2CPDK2PRF1CHEK1ALDH1A1 | |
| SCHEMBL21546488 | 0.89 | ELANE (0.36) | ADRA2CBRD4PTGER4PRF1ADORA2A | |
| SCHEMBL22760910 | 0.89 | CHEK1 (0.35) | ADRA2CBRD4PTGER4PDK2PRF1 | |
| SCHEMBL22760887 | 0.89 | CHEK1 (0.35) | ADRA2CPTGER4PDK2PRF1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478793-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |