Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 6/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621477 | 0.81 | TDP1 (0.41) | ACMSDMCL1DHFRHNF4AALDH1A1 | |
| SCHEMBL112399 | 0.76 | LMNA (0.55) | ALDH1A1TP53HSD17B10CA12CA1 | |
| SCHEMBL10408835 | 0.75 | LMNA (0.53) | ALDH1A1TP53HSD17B10CA12CA1 | |
| SCHEMBL10728223 | 0.74 | CA12 (0.68) | ALDH1A1TP53HSD17B10CA12CA1 | |
| SCHEMBL8373102 | 0.73 | ACMSD (0.67) | ACMSDMCL1DHFRHNF4AGSTA1 | |
| SCHEMBL7670373 | 0.72 | PTPN5 (0.59) | PTPN5RXRARXRBRXRGAPP | |
| SCHEMBL10727310 | 0.72 | CA12 (0.67) | ALDH1A1TP53HSD17B10CA12CA1 | |
| SCHEMBL29860848 | 0.71 | BRD4 (0.56) | PTPN5RXRARXRBRXRGAPP | |
| SCHEMBL2730419 | 0.70 | ACMSD (0.66) | ACMSDMCL1DHFRHNF4AALDH1A1 | |
| SCHEMBL9655482 | 0.70 | PPARG (0.41) | ALDH1A1TP53HSD17B10RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564206-A1 | NOVEL POLYMERISABLE MONOMERS AND THEIR USE AS REACTIVE DILUENTS IN CURABLE COMPOSITIONS | Align Technology, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |