Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810703 | 0.73 | PARP1 (0.37) | TP53PARP1 | |
| SCHEMBL28791541 | 0.64 | TP53 (0.43) | TP53PARP1 | |
| Trifluoroacetic Acid SCHEMBL3816984 | 0.63 | PARP1 (0.36) | PARP1 | |
| SCHEMBL16801723 | 0.63 | OPRM1 (0.65) | — | |
| SCHEMBL7539678 | 0.61 | CRBN (0.42) | — | |
| SCHEMBL10447583 | 0.61 | KDM4E (0.31) | — | |
| SCHEMBL2851425 | 0.60 | CDA (0.41) | TP53PARP1 | |
| SCHEMBL11387896 | 0.60 | TP53 (0.45) | TP53 | |
| SCHEMBL21919625 | 0.59 | TP53 (0.31) | TP53 | |
| SCHEMBL13655800 | 0.59 | MAPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |