Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656015 | 0.73 | TP53 (0.33) | — | |
| SCHEMBL1810703 | 0.67 | PARP1 (0.37) | MAPK1 | |
| SCHEMBL18930924 | 0.65 | — | — | |
| SCHEMBL21966233 | 0.61 | JAK2 (0.33) | — | |
| SCHEMBL21547898 | 0.59 | TP53 (0.33) | — | |
| SCHEMBL21118773 | 0.58 | — | — | |
| SCHEMBL2100919 | 0.58 | BRD4 (0.50) | MAPK1 | |
| SCHEMBL31184539 | 0.58 | BRD4 (0.50) | MAPK1 | |
| SCHEMBL31184549 | 0.58 | BRD4 (0.50) | MAPK1 | |
| SCHEMBL14163377 | 0.58 | PARP1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108648-A1 | Selected CGRP antagonists, method for their manufacture and use as medicines | Boehringer Ingelheim International GmbH (DE) | 2009-10-14 | — | — | EP | disclosed |