Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 18/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548047 | 1.00 | OGFRL1 (0.49) | OGFRL1OPRM1OPRK1OPRD1NR1H4 | |
| SCHEMBL10285467 | 0.80 | OGFRL1 (0.50) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL22225553 | 0.80 | OGFRL1 (0.51) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL16382145 | 0.76 | OGFRL1 (0.59) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL20206668 | 0.76 | ALDH1A1 (0.53) | OGFRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL19861061 | 0.76 | OGFRL1 (0.53) | OGFRL1OPRM1OPRK1OPRD1NR1H4 | |
| SCHEMBL22225559 | 0.74 | OGFRL1 (0.51) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL21547991 | 0.73 | OGFRL1 (0.45) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL13904386 | 0.73 | OGFRL1 (0.54) | OGFRL1OPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL16382068 | 0.72 | OGFRL1 (0.53) | OGFRL1OPRM1OPRK1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |